Research

Photobiomodulation also known as Light Therapy and Laser Therapy has been researched for decades around the world. There are thousands of published studies exploring the impact of light on the body.

Low level laser therapy for the patients with painful diabetic peripheral neuropathy – A systematic review

Received 28 June 2019, Accepted 12 July 2019, Available online 13 July 2019.

Low Level Laser Therapy (LLLT) is an emerging treatment modality for management of neuropathic pain. It works by triggering biochemical changes with in cells.

The effect of photobiomodulation on chemotherapy-induced peripheral neuropathy: A randomized, sham-controlled clinical trial

Received 22 November 2019, Accepted 12 November 2019, Available online 13 November 2019.

Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of cancer therapy with few efficacious treatments.

Therapeutic Efficacy of Home-Use Photobiomodulation Devices: A Systematic Literature Review

Published Online:14 Jan 2019

Home-use PBM devices have been marketed for cosmetic and therapeutic purposes. This is the first systematic literature review for nonesthetic applications.

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Prolotherapy and Low Level Laser Therapy: A Synergistic Approach to Pain Management in Chronic Osteoarthritis

Published online 2017 October 15

Regenerative injection therapy and low level laser therapy are alternative remedies known for their success in the treatment and symptomatic management of chronic musculoskeletal conditions.

Efficacy of low level laser therapy on painful diabetic peripheral neuropathy

Published online 2015 October 2

Diabetic peripheral neuropathy (DPN) accounts for most common complications of T2DM. Painful DPN is associated with functional limitation & poor quality of life. Therefore, objective of the study is to find the effect of low level laser therapy on painful diabetic peripheral neuropathy (DPN) in type 2 diabetes mellitus (T2DM)

The Use of Low Level Laser Therapy (LLLT) For Musculoskeletal Pain

Published online 2015 June 9

Pain is the most common reason for physician consultation in the United States. One out of three Americans is affected by chronic pain annually. The number one reason for missed work or school days is musculoskeletal pain.

The Effectiveness of Photobiomodulation Therapy Versus Cryotherapy for Skeletal Muscle Recovery: A Critically Appraised Topic

Received 2019 July 1, Available online 2019 January 29.

Cryotherapy is one of the most commonly used modalities for postexercise muscle recovery despite inconsistencies in the literature validating its effectiveness.

Noninvasive red and near-infrared wavelength- induced photobiomodulation: promoting impaired cutaneous wound healing

First published: 10 December 2016

The innumerable intricacies associated with chronic wounds have made the development of new painless, noninvasive, biophysical therapeutic interventions as the focus of current biomedical research. Red and near-infrared light-induced photobiomodulation therapy…

Effect of near-infrared light-emitting diodes on nerve regeneration

Received 2010 March 15, Available online 2010 April 1

Photobiomodulation by red to near-infrared light-emitting diodes (LEDs) has been reported to accelerate wound healing, attenuate degeneration of an injured optic nerve, and promote tissue growth.

The restorative effects of pulsed infrared light therapy on significant loss of peripheral protective sensation in patients with long-term type 1 and type 2 diabetes mellitus

Published online 2006 May 1

Pulsed infrared light therapy (PILT) has been shown to increase peripheral sensation in diabetic patients with diabetic peripheral neuropathy (DPN).

Use of near-infrared light to reduce symptoms associated with restless legs syndrome in a woman: a case report

Published online 2010 August 23

We describe a potential new treatment option for patients suffering from restless legs syndrome.

Mitochondrial Mechanisms of Photobiomodulation in Context of New Data About Multiple Roles of ATP

Published online 2010 August 23

Various cellular responses to visible and IR-A radia-tion have been studied for decades in the context of molecular mechanisms of laser phototherapy [also called photobiomodulation, low-level light therapy (LLLT)].

Phototherapy promotes healing of chronic diabetic leg ulcers that failed to respond to other therapies

Published online 2009 August 6

We tested the hypothesis that combined 660 and 890 nm LED phototherapy will promote healing of diabetic ulcers that failed to respond to other forms of treatment.

Mechanisms of action for light therapy: a review of molecular interactions

Published online 2010 Aug 23

Five decades after the first documented use of a laser for wound healing, research in light therapy has yet to elucidate the
underlying biochemical pathways causing its effects.

Infrared therapy for chronic low back pain: A randomized, controlled trial

Published online 2021 October 14

The objective of the present study was to assess the degree of pain relief obtained by applying infrared (IR) energy to the low back in patients with chronic, intractable low back pain.

Phototherapy with LED Shows Promising Results in Healing Chronic Wounds in Diabetes Mellitus Patients: A Prospective Randomized Double-Blind Study

Received 2018 July 7, Available online 2018 April 18

The study examined the influence of phototherapy with light-emitting diodes (LEDs) on chronic diabetic wound healing.

Laser Photobiomodulation: Models and Mechanisms

Published online 2019 February 19

The overwhelming clinical evidence of the clinical effectiveness of low-level laser therapy (LLLT) therapy has been balanced by few reports of equivocal or nonefficacious studies.

The Use of Low Level Laser Therapy (LLLT) For Musculoskeletal Pain

Published online 2015 June 9

Pain is the most common reason for physician consultation in the United States. One out of three Americans is affected by chronic pain annually. The number one reason for missed work or school days is musculoskeletal pain.

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